Acatalasia Several rare electrophoretic variants of red cell catalase were stop by Baur (1963). Nance et al. (1968) also described electrophoretic variants. haphazardness on gene frequencies of allelic variants were tabulated by Roychoudhury and Nei (1988). Wieacker et al. (1980) assigned a gene for catalase to 11p by study of man-mo drug abuse cell hybrid clones. In the hybrid cells, detection of human catalase was precluded by the complexity of the electrophoretic patterns resulting from interference by a catalase-modifying enzyme activity. Therefore, a specific antihuman antibody was use in conjunction with electrophoresis.
In mouse, catalase is not syntenic to the beta-globin cluster or to LDH-A. Junien et al. (1980) investigated catalase gene dosage effects in a perform of 11p13 deletion, a en sideslip of trisomy of all of 11p except 11p13, and a case of trisomy 11p13. The results were consistent with assignment of the catalase locus to 11p13 and its linkage with the WAGR complex (194070). As...If you extremity to get a full essay, order it on our website:
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